Article
Platelet CD36 surface expression levels affect functional responses to oxidized LDL and are associated with inheritance of specific genetic polymorphisms.
Blood - 9 Jun 2011
Ghosh Arunima, Murugesan Gurunathan, Chen Kan, Zhang Li, Wang Qing, Febbraio Maria, Anselmo Rita Marie, Marchant Kandice, Barnard John, Silverstein Roy L
Abstract excerpt
CD36 modulates platelet function via binding to oxidized LDL (oxLDL), cell-derived microparticles, and thrombospondin-1. We hypothesized that the level of platelet CD36 expression may be associated with inheritance of specific genetic polymorphisms and that this would determine platelet reactivit...
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