Article
A genetic association study of D-dimer levels with 50K SNPs from a candidate gene chip in four ethnic groups.
Thrombosis research - 1 Aug 2014
Weng Lu-Chen, Tang Weihong, Rich Stephen S, Smith Nicholas L, Redline Susan, O'Donnell Christopher J, Basu Saonli, Reiner Alexander P, Delaney Joseph A, Tracy Russell P, Palmer Cameron D, Young Taylor, Yang Qiong, Folsom Aaron R, Cushman Mary
Abstract excerpt
INTRODUCTION: D-dimer, a fibrin degradation product, is related to risk of cardiovascular disease and venous thromboembolism. Genetic determinants of D-dimer are not well characterized; notably, few data have been reported for African American (AA), Asian, and Hispanic populations. MATERIALS AND METHODS: We conducted a large-scale candidate gene association study to identify variants in genes associated with...
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