Article
Vitamin D Binding Protein rs7041 polymorphism and high-residual platelet reactivity in patients receiving dual antiplatelet therapy with clopidogrel or ticagrelor.
Vascular pharmacology - 1 Aug 2017
Verdoia Monica, Daffara Veronica, Pergolini Patrizia, Rolla Roberta, Marino Paolo, Bellomo Giorgio, Carriero Alessandro, De Luca Giuseppe
Abstract excerpt
BACKGROUND: Vitamin D deficiency represents a major health problem in general population, especially for its association with cardiovascular disorders and thrombotic risk, even in patients on dual antiplatelet therapy (DAPT). Vitamin D Binding Protein (VDBP) is the main transporter of vitamin D in the bloodstream and genetic polymorphisms of this protein have been shown to account for a significant variability of...
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