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Article

The Inter-Relationship of Platelets with Interleukin-1β-Mediated Inflammation in Humans

19 Nov 2018

Abstract excerpt

BACKGROUND: Inflammation and coagulation are key processes in cardiovascular diseases (CVDs). The Canakinumab Anti-inflammatory Thrombosis Outcome Study trial affirmed the importance of inflammation in CVD by showing that inhibition of the interleukin (IL)-1β pathway prevents recurrent CVD. A bi-directional relationship exists between inflammation and coagulation, but the precise interaction of platelets and...

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PMID: 30453346
DOI: 10.1055/s-0038-1675603

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