Article
TS: a powerful truncated test to detect novel disease associated genes using publicly available gWAS summary data.
BMC bioinformatics - 4 May 2020
Zhang Jianjun, Guo Xuan, Gonzales Samantha, Yang Jingjing, Wang Xuexia
Abstract excerpt
BACKGROUND: In the last decade, a large number of common variants underlying complex diseases have been identified through genome-wide association studies (GWASs). Summary data of the GWASs are freely and publicly available. The summary data is usually obtained through single marker analysis. Gene-based analysis offers a useful alternative and complement to single marker analysis. Results from gene level...
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