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Article

Fast set-based association analysis using summary data from GWAS identifies novel gene loci for human complex traits.

Scientific reports - 8 Sept 2016

Bakshi Andrew, Zhu Zhihong, Vinkhuyzen Anna A E, Hill W David, McRae Allan F, Visscher Peter M, Yang Jian

Abstract excerpt

We propose a method (fastBAT) that performs a fast set-based association analysis for human complex traits using summary-level data from genome-wide association studies (GWAS) and linkage disequilibrium (LD) data from a reference sample with individual-level genotypes. We demonstrate using simulations and analyses of real datasets that fastBAT is more accurate and orders of magnitude faster than the prevailing...

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Identifiers

PMID: 27604177
DOI: 10.1038/srep32894
PMCID: PMC5015118

Genes

FOXP1
THRB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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