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Gene-based association tests using GWAS summary statistics

11 Mar 2019

Abstract excerpt

MOTIVATION: A huge number of genome-wide association studies (GWAS) summary statistics freely available in databases provide a new material for gene-based association analysis aimed at identifying rare genetic variants. Only a few of the many popular gene-based methods developed for individual genotype and phenotype data are adapted for the practical use of the GWAS summary statistics as input. RESULTS: We...

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PMID: 30860568
DOI: 10.1093/bioinformatics/btz172

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