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Article

Comparative genomics reveals new single-nucleotide polymorphisms that can assist in identification of adherent-invasive Escherichia coli.

Scientific reports - 9 Feb 2018

Camprubí-Font Carla, Lopez-Siles Mireia, Ferrer-Guixeras Meritxell, Niubó-Carulla Laura, Abellà-Ametller Carles, Garcia-Gil Librado Jesús, Martinez-Medina Margarita

Abstract excerpt

Adherent-invasive Escherichia coli (AIEC) have been involved in Crohn's disease (CD). Currently, AIEC are identified by time-consuming techniques based on in vitro infection of cell lines to determine their ability to adhere to and invade intestinal epithelial cells as well as to survive and replicate within macrophages. Our aim was to find signature sequences that can be used to identify the AIEC pathotype....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29426864
DOI: 10.1038/s41598-018-20843-x
PMCID: PMC5807354

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