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Article

Polymorphisms in CRYBB2 encoding βB2-crystallin are associated with antisaccade performance and memory function.

Translational psychiatry - 21 Apr 2020

Giegling Ina, Hartmann Annette M, Genius Just, Konte Bettina, Maul Stephan, Straube Andreas, Eggert Thomas, Mulert Christoph, Leicht Gregor, Karch Susanne, Hegerl Ulrich, Pogarell Oliver, Hölter Sabine M, Möller Hans-Jürgen, Graw Jochen, Rujescu Dan

Abstract excerpt

βB2-crystallin (gene symbol: Crybb2/CRYBB2) was first described as a structural protein of the ocular lens before it was detected in various brain regions of the mouse, including the hippocampus and the cerebral cortex. Mutations in the mouse Crybb2 gene lead to alterations of sensorimotor gating measured as prepulse inhibition (PPI) and reduced hippocampal size, combined with an altered number of...

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Identifiers

PMID: 32317624
DOI: 10.1038/s41398-020-0791-0
PMCID: PMC7174396

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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