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Article

Bipolar disorder ANK3 risk variant effect on sustained attention is replicated in a large healthy population.

Psychiatric genetics - 1 Aug 2012

Hatzimanolis Alex, Smyrnis Nikolaos, Avramopoulos Dimitrios, Stefanis Costas N, Evdokimidis Ioannis, Stefanis Nicholas C

Abstract excerpt

Independent genome-wide association studies have implicated a common single nucleotide polymorphism within the ANK3 gene (rs10994336) in bipolar disorder (BD) susceptibility, thus establishing rs10994336 marker as a strong candidate predisposing genetic factor for BD. Furthermore, recent findings demonstrate that this variant impacts on cognitive functioning in BD patients, their unaffected relatives, and healthy...

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Identifiers

PMID: 22498896
DOI: 10.1097/YPG.0b013e328353ae79
PMCID: PMC5744587

Genes

ANK3

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Source receipt: pubmed, retrieved 7 Sept 2026.

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