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Article

Contribution of genes in the GABAergic pathway to bipolar disorder and its executive function deficit in the Chinese Han population.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jan 2018

Ren Hongyan, Guan Lijie, Zhao Liansheng, Lin Yin, Wang Yincheng, Yang Zhenxing, Li Xuan, Ma Xiaohong, Cheng Xiongchao, Deng Wenhao, Aitchison Katherine J, Cao Liping, Li Tao

Abstract excerpt

In this study, we investigated the association between bipolar I disorder (BDI) and between cognitive deficits therein and SNPs in GABAergic receptor genes. The sample comprised 477 patients with BDI and 438 healthy controls, with three neurocognitive tests being administered in 123 patients and 164 controls. For three SNPs, rs505474, rs1398175, and rs4868029 in the GABRA2, GABRA4, and GABRP genes, respectively,...

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Source

Identifiers

PMID: 29135068
DOI: 10.1002/ajmg.b.32601

Genes

GABRB3
GABRP
GABRA2
GABRA4
GABRA6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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