Article
Crybb2 coding for βB2-crystallin affects sensorimotor gating and hippocampal function.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Oct 2013
Sun Minxuan, Hölter Sabine M, Stepan Jens, Garrett Lillian, Genius Just, Kremmer Elisabeth, Hrabě de Angelis Martin, Wurst Wolfgang, Lie D Chichung, Bally-Cuif Laure, Eder Matthias, Rujescu Dan, Graw Jochen
Abstract excerpt
βB2-crystallin (gene symbol: Crybb2/CRYBB2) was first described as a structural protein of the ocular lens. This gene, however, is also expressed in several regions of the mammalian brain, although its function in this organ remains entirely unknown. To unravel some aspects of its function in the brain, we combined behavioral, neuroanatomical, and physiological analyses in a novel Crybb2 mouse mutant, O377....
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