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Article

Novel allele of crybb2 in the mouse and its expression in the brain.

Investigative ophthalmology & visual science - 1 Apr 2008

Ganguly Koustav, Favor Jack, Neuhäuser-Klaus Angelika, Sandulache Rodica, Puk Oliver, Beckers Johannes, Horsch Marion, Schädler Sandra, Vogt Weisenhorn Daniela, Wurst Wolfgang, Graw Jochen

Abstract excerpt

PURPOSE: O377 was identified as a new dominant cataract mutation in mice after radiation experiments. The purpose of this study was to genetically characterize the mutation and to analyze its biological consequences. METHODS: Linkage analysis of the O377 mouse mutant was performed; candidate genes including Crybb2 were sequenced. The authors analyzed eyes and brains of the mutants by histology and the expression...

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PMID: 18385073
DOI: 10.1167/iovs.07-0788

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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