Article
Genetic Selection Based on a Ste6*C-HA-Ura3 Substrate Identifies New Cytosolic Quality Control Alleles in Saccharomyces cerevisiae.
G3 (Bethesda, Md.) - 1 Jun 2020
Chan Shu Ning, Prasad Rupali, Matsudaira Paul
Abstract excerpt
Protein quality control in the cytosol (CytoQC) is an important cellular pathway consisting of a network of components which monitor the folding of cytosolic proteins and ensure the efficient removal of aberrant ones. Our understanding of CytoQC mechanisms is limited in part by the ability of current approaches to identify new genes in the pathway. In this study, we developed a CytoQC reporter substrate,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
