Article
The Genetic Basis of Thyroid Function: Novel Findings and New Approaches.
The Journal of clinical endocrinology and metabolism - 1 Jun 2020
Kuś Aleksander, Chaker Layal, Teumer Alexander, Peeters Robin P, Medici Marco
Abstract excerpt
CONTEXT: Genetic factors are major determinants of thyroid function. Over the last two decades, multiple genetic variants have been associated with variations in normal range thyroid function tests. Most recently, a large-scale genome-wide association study (GWAS) doubled the number of known variants associated with normal range thyrotropin (TSH) and free thyroxine (FT4) levels. EVIDENCE ACQUISITION: This review...
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