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Article

A locus on chromosome 1p36 is associated with thyrotropin and thyroid function as identified by genome-wide association study.

American journal of human genetics - 10 Sept 2010

Panicker Vijay, Wilson Scott G, Walsh John P, Richards J Brent, Brown Suzanne J, Beilby John P, Bremner Alexandra P, Surdulescu Gabriela L, Qweitin Emad, Gillham-Nasenya Irina, Soranzo Nicole, Lim Ee M, Fletcher Stephen J, Spector Tim D

Abstract excerpt

Thyroid hormones are key regulators of cellular growth, development, and metabolism, and thyroid disorders are a common cause of ill health in the community. Circulating concentrations of thyrotropin (TSH), thyroxine (T4) and triiodothyronine (T3) have a strong heritable component and are thought to be under polygenic control, but the genes responsible are mostly unknown. In order to identify genetic loci...

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Identifiers

PMID: 20826269
DOI: 10.1016/j.ajhg.2010.08.005
PMCID: PMC2933351

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CAPZB

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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