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Article

Genetics of Thyroid Function: Relevance for Biology and Disease Management.

The Journal of clinical endocrinology and metabolism - 18 Dec 2025

Sterenborg Rosalie B T M, Peeters Robin P, Visser Edward, Kuś Aleksander, Smit Jan W A, Teumer Alexander, Medici Marco

Abstract excerpt

CONTEXT: Genetic factors are a major contributor to variation in thyroid function. Recent studies have partly identified the responsible common genetic variants and studied their application in unraveling thyroid (patho)physiology as well as their potential clinical use. EVIDENCE ACQUISITION: This review summarizes the current state of knowledge regarding the genetic architecture of thyroid function as well as...

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Identifiers

PMID: 41252260
DOI: 10.1210/clinem/dgaf491
PMCID: PMC12712998

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