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Article

DNA methylation profiling identifies a high effect genetic variant for lipoprotein(a) levels.

Epigenetics - 1 Sept 2020

Jones Gregory T, Marsman Judith, Bhat Basharat, Phillips Victoria L, Chatterjee Aniruddha, Rodger Euan J, Williams Michael J A, van Rij André M, McCormick Sally P A

Abstract excerpt

Changes in whole blood DNA methylation levels at several CpG sites have been associated with circulating blood lipids, specifically high-density lipoprotein and triglycerides. This study performs a discovery and validation epigenome-wide association study (EWAS) for circulating lipoprotein(a) [Lp(a)], an independent risk factor for cardiovascular diseases. Whole-blood DNA methylation profiles were assessed in a...

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Source

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Identifiers

PMID: 32237968
DOI: 10.1080/15592294.2020.1739797
PMCID: PMC7518699

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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