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Article

A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms.

Journal of lipid research - 1 Sept 2017

Mack Salome, Coassin Stefan, Rueedi Rico, Yousri Noha A, Seppälä Ilkka, Gieger Christian, Schönherr Sebastian, Forer Lukas, Erhart Gertraud, Marques-Vidal Pedro, Ried Janina S, Waeber Gerard, Bergmann Sven, Dähnhardt Doreen, Stöckl Andrea, Raitakari Olli T, Kähönen Mika, Peters Annette, Meitinger Thomas, Strauch Konstantin, Kedenko Ludmilla, Paulweber Bernhard, Lehtimäki Terho, Hunt Steven C, Vollenweider Peter, Lamina Claudia, Kronenberg Florian

Abstract excerpt

High lipoprotein (a) [Lp(a)] concentrations are an independent risk factor for cardiovascular outcomes. Concentrations are strongly influenced by apo(a) kringle IV repeat isoforms. We aimed to identify genetic loci associated with Lp(a) concentrations using data from five genome-wide association studies (n = 13,781). We identified 48 independent SNPs in the LPA and 1 SNP in the APOE gene region to be...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 28512139
DOI: 10.1194/jlr.M076232
PMCID: PMC5580897

Genes

LPA
APOE
CAD
MAF
TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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