Article
Roles for T and NK cells in the innate immune response to Shigella flexneri.
Journal of immunology (Baltimore, Md. : 1950) - 1 Aug 2005
Le-Barillec Karine, Magalhaes Joao Gamelas, Corcuff Erwan, Thuizat Audrey, Sansonetti Philippe J, Phalipon Armelle, Di Santo James P
Abstract excerpt
Shigella flexneri, an enteroinvasive Gram-negative bacterium, is responsible for the worldwide endemic form of bacillary dysentery. The host response to primary infection is characterized by the induction of an acute inflammation, which is accompanied by polymorphonuclear cell (PMN) infiltration, resulting in massive destruction of the colonic mucosa. However, PMN play a major role in the recovery from primary...
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