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Article

Follicular regulatory helper T cells control the response of regulatory B cells to a high-cholesterol diet.

Cardiovascular research - 22 Feb 2021

Burger Fabienne, Miteva Kapka, Baptista Daniela, Roth Aline, Fraga-Silva Rodrigo A, Martel Catherine, Stergiopulos Nikolaos, Mach François, Brandt Karim J

Abstract excerpt

AIMS: B cell functions in the process of atherogenesis have been investigated but several aspects remain to be clarified. METHODS AND RESULTS: In this study, we show that follicular regulatory helper T cells (TFR) control regulatory B cell (BREG) populations in Apoe-/- mice models on a high-cholesterol diet (HCD). Feeding mice with HCD resulted in up-regulation of TFR and BREG cell populations, causing the...

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Identifiers

PMID: 32219371
DOI: 10.1093/cvr/cvaa069
PMCID: PMC7898950

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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