Article
B regulatory cells are increased in hypercholesterolaemic mice and protect from lesion development via IL-10.
Thrombosis and haemostasis - 1 Oct 2015
Strom Asa C, Cross Amanda J, Cole Jennifer E, Blair Paul A, Leib Christoph, Goddard Michael E, Rosser Elizabeth C, Park Inhye, Hultgårdh Nilsson Anna, Nilsson Jan, Mauri Claudia, Monaco Claudia
Abstract excerpt
Whilst innate B1-B cells are atheroprotective, adaptive B2-B cells are considered pro-atherogenic. Different subsets of B regulatory cells (B(reg)) have been described. In experimental arthritis and lupus-like disease, B(reg) are contained within the CD21(hi)CD23(hi)CD24(hi) B cell pool. The existence and role of B(reg) in vascular disease is not known. We sought to investigate the existence, identity and...
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