Article
Cellular immunity, low-density lipoprotein and atherosclerosis: break of tolerance in the artery wall.
Thrombosis and haemostasis - 1 Nov 2011
Ketelhuth D F J, Hansson G K
Abstract excerpt
Atherosclerosis is a chronic inflammatory disease. Atherosclerotic plaques contain abundant immune cells that can dictate and effect inflammatory responses. Among them, T cells are present during all stages of the disease suggesting that they are essential in the initiation as well as the progression of plaque. Experimental as well as clinical research has demonstrated different T cell subsets, i.e. CD4+ Th1,...
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