Article
Treating atherosclerosis with regulatory T cells.
Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2015
Foks Amanda C, Lichtman Andrew H, Kuiper Johan
Abstract excerpt
Regulatory T cells (Tregs) play an important role in the regulation of T-cell-mediated immune responses through suppression of T-cell proliferation and secretion of inhibitory cytokines, such as interleukin-10 and transforming growth factor-β. Impaired Treg numbers and function have been associated with numerous diseases, and an imbalance between proinflammatory/proatherogenic cells and Tregs promotes...
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