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Article

Follicular B Cells Promote Atherosclerosis via T Cell-Mediated Differentiation Into Plasma Cells and Secreting Pathogenic Immunoglobulin G.

Arteriosclerosis, thrombosis, and vascular biology - 1 May 2018

Tay Christopher, Liu Yu-Han, Kanellakis Peter, Kallies Axel, Li Yi, Cao Anh, Hosseini Hamid, Tipping Peter, Toh Ban-Hock, Bobik Alex, Kyaw Tin

Abstract excerpt

OBJECTIVE: B cells promote or protect development of atherosclerosis. In this study, we examined the role of MHCII (major histocompatibility II), CD40 (cluster of differentiation 40), and Blimp-1 (B-lymphocyte-induced maturation protein) expression by follicular B (FO B) cells in development of atherosclerosis together with the effects of IgG purified from atherosclerotic mice. APPROACH AND RESULTS: Using mixed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 29599140
DOI: 10.1161/ATVBAHA.117.310678

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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