Article
Discovery and Differential Processing of HLA Class II-Restricted Minor Histocompatibility Antigen LB-PIP4K2A-1S and Its Allelic Variant by Asparagine Endopeptidase.
Frontiers in immunology - 1 Jan 2020
Kremer Anita N, Bausenwein Judith, Lurvink Ellie, Kremer Andreas E, Rutten Caroline E, van Bergen Cornelis A M, Kretschmann Sascha, van der Meijden Edith, Honders Maria W, Mazzeo Daniela, Watts Colin, Mackensen Andreas, Falkenburg J H Frederik, Griffioen Marieke
Abstract excerpt
Minor histocompatibility antigens are the main targets of donor-derived T-cells after allogeneic stem cell transplantation. Identification of these antigens and understanding their biology are a key requisite for more insight into how graft vs. leukemia effect and graft vs. host disease could be separated. We here identified four new HLA class II-restricted minor histocompatibility antigens using whole genome...
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