Article
Identification of minor histocompatibility antigens based on the 1000 Genomes Project.
Haematologica - 1 Dec 2014
Oostvogels Rimke, Lokhorst Henk M, Minnema Monique C, van Elk Maureen, van den Oudenalder Kelly, Spierings Eric, Mutis Tuna, Spaapen Robbert M
Abstract excerpt
Minor histocompatibility antigens are highly immunogeneic polymorphic peptides playing crucial roles in the clinical outcome of HLA-identical allogeneic stem cell transplantation. Although the introduction of genome-wide association-based strategies significantly has accelerated the identification of minor histocompatibility antigens over the past years, more efficient, rapid and robust identification techniques...
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