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Article

Characterization of Human Leukocyte Antigen (HLA) Proteins with Integrated Immunopeptidomics and Proteomics Approach.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2026

Chen Rui, Li Jianjun

Abstract excerpt

Killing of cancer cells by cytotoxic Tcells requires efficient presentation of tumor antigens by human leukocyte antigen (HLA) molecules and patient-specific HLA genotypes also influence response to immune checkpoint inhibitors. Genotyping for a specific HLA allele can be used as biomarker to predict the immunotherapy outcome of a patient. Traditionally, HLA genotyping is achieved by sequencing the genome or...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 41085623
DOI: 10.1007/978-1-0716-4832-2_9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 11 Sept 2026.

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