Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of apolipoprotein E ε4 allele on the progression of cognitive decline in the early stage of Alzheimer's disease

1 Jan 2020

Abstract excerpt

Abstract Introduction Possession of the apolipoprotein E ( APO E ) ε4 allele advances amyloid β (Aβ) deposition and symptomatic onset of Alzheimer's disease (AD), whereas its effect on the rate of cognitive decline remained controversial. We examined the effects of APOE ε4 allele on cognition in biomarker‐confirmed late mild cognitive impairment (LMCI) and mild AD subjects in the Japanese Alzheimer's Disease...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Dementia and Cognitive Impairment Research
Share to Neurological Disease Mechanisms and Treatments

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32211510
DOI: 10.1002/trc2.12007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 18 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of apolipoprotein E ε4 allele on the progression of cognitive decline in the early stage of Alzheimer's diseasePMID 32211510Read ↗

Predictive value of APOE-ε4 allele for progression from MCI to AD-type dementia: a meta-analysis.Semantic proximity Read ↗

APOE4 genotypes and the trajectory of biomarkers, neuroimaging, and cognitive measures in Alzheimer's Disease: A mixed-effects disease progression model.Semantic proximity Read ↗

Accelerated progression from mild cognitive impairment to dementia among APOE ε4ε4 carriers.Semantic proximity Read ↗

The apolipoprotein E genotype predicts longitudinal transitions to mild cognitive impairment but not to Alzheimer's dementia: findings from a nationally representative study.Semantic proximity Read ↗

Distribution and clinical impact of apolipoprotein E4 in subjective memory impairment and early mild cognitive impairment.Semantic proximity Read ↗

Apolipoprotein E genotypes and plasma levels in mild cognitive impairment conversion to Alzheimer's disease: A follow-up study.Semantic proximity Read ↗

Amyloid and APOE ε4 interact to influence short-term decline in preclinical Alzheimer disease.Semantic proximity Read ↗

APOE ε4 increases the risk of progression from amnestic mild cognitive impairment to Alzheimer's disease among ethnic Chinese in Taiwan.Semantic proximity Read ↗

Age‐dependent effects of <i>APOE</i> ε4 in preclinical Alzheimer's diseaseSemantic proximity Read ↗

Neuropathology-Independent Association Between APOE Genotype and Cognitive Decline Rate in the Normal Aging-Early Alzheimer ContinuumSemantic proximity Read ↗

APOE ε2ε4 genotype, incident AD and MCI, cognitive decline, and AD pathology in older adults.Semantic proximity Read ↗

The Effect of the APOE ε2ε4 Genotype on the Development of Alzheimer's Disease (AD) and Mild Cognitive Impairment (MCI) in Non-Latino Whites.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.