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Article

Predictive value of APOE-ε4 allele for progression from MCI to AD-type dementia: a meta-analysis.

Journal of neurology, neurosurgery, and psychiatry - 1 Oct 2011

Elias-Sonnenschein Lyzel S, Viechtbauer Wolfgang, Ramakers Inez H G B, Verhey Frans R J, Visser Pieter Jelle

Abstract excerpt

BACKGROUND: The identification of subjects with mild cognitive impairment (MCI) at high risk for Alzheimer's disease (AD) is important for prognosis and early intervention. The APOE-ε4 allele is the strongest known genetic risk factor for AD. The authors performed a meta-analysis to establish the predictive accuracy of the APOE-ε4 allele for progression from MCI to AD-type dementia. METHODS: The authors included...

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Source

Identifiers

PMID: 21493755
DOI: 10.1136/jnnp.2010.231555

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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