Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Distribution and clinical impact of apolipoprotein E4 in subjective memory impairment and early mild cognitive impairment.

Scientific reports - 7 Aug 2020

Cho Hanna, Kim Young-Eun, Chae Wonjeong, Kim Ko Woon, Kim Jong-Won, Kim Hee Jin, Na Duk L, Ki Chang-Seok, Seo Sang Won

Abstract excerpt

The apolipoprotein E (APOE) e4 allele is the most common genetic variant associated with Alzheimer's disease (AD). We sought to investigate the distribution of APOE genotypes across the full clinical AD spectrum including AD, late-stage amnestic mild cognitive impairment (L-aMCI), early-stage aMCI (E-aMCI), subjective memory impairment (SMI), and controls. We prospectively recruited 713 AD patients, 735 aMCI...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Alleles

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Alzheimer Disease

Share to Apolipoprotein E4

Share to Case-Control Studies

Share to Gene Frequency

Share to Genotype

Share to Neuropsychological Tests

Source

Open in PubMed Open full text

Identifiers

PMID: 32770103
DOI: 10.1038/s41598-020-69603-w
PMCID: PMC7414226

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Distribution and clinical impact of apolipoprotein E4 in subjective memory impairment and early mild cognitive impairment.PMID 32770103Read ↗

Apolipoprotein E genotypes and plasma levels in mild cognitive impairment conversion to Alzheimer's disease: A follow-up study.Semantic proximity Read ↗

Effect of apolipoprotein E ε4 allele on the progression of cognitive decline in the early stage of Alzheimer's diseaseSemantic proximity Read ↗

APOE-related risk of mild cognitive impairment and dementia for prevention trials: An analysis of four cohorts.Semantic proximity Read ↗

Influence of apolipoprotein E varepsilon4 on rates of cognitive and functional decline in mild cognitive impairment.Semantic proximity Read ↗

Distribution of APOE genotypes in a memory clinic cohort.Semantic proximity Read ↗

Impact of APOE in mild cognitive impairment.Semantic proximity Read ↗

APOE ε4 Allele Distribution and Association With Scores of Subjective Cognitive Decline Questionnaire 9 in a Large Chinese Memory Clinic CohortSemantic proximity Read ↗

APOE ε4 increases the risk of progression from amnestic mild cognitive impairment to Alzheimer's disease among ethnic Chinese in Taiwan.Semantic proximity Read ↗

Impact of apolipoprotein E isoforms on sporadic Alzheimer’s diseaseSemantic proximity Read ↗

Effects of apolipoprotein E-epsilon4 and -epsilon2 in amnestic mild cognitive impairment and dementia in Shanghai: SCOBHI-P.Semantic proximity Read ↗

APOE4 genotypes and the trajectory of biomarkers, neuroimaging, and cognitive measures in Alzheimer's Disease: A mixed-effects disease progression model.Semantic proximity Read ↗

Apolipoprotein E e4 Allele Is Associated with Subjective Cognitive Decline: A Meta-Analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.