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Article

Border forces and friction control epithelial closure dynamics.

Biophysical journal - 7 Jan 2014

Cochet-Escartin Olivier, Ranft Jonas, Silberzan Pascal, Marcq Philippe

Abstract excerpt

We study the closure dynamics of a large number of well-controlled circular apertures within an epithelial monolayer, where the collective cell migration responsible for epithelization is triggered by the removal of a spatial constraint rather than by scratching. Based on experimental observations, we propose a physical model that takes into account border forces, friction with the substrate, and tissue rheology....

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Identifiers

PMID: 24411238
DOI: 10.1016/j.bpj.2013.11.015
PMCID: PMC3907253

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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