Article
Mechanics of soft epithelial keratin networks depend on modular filament assembly kinetics.
Acta biomaterialia - 1 Oct 2016
Deek Joanna, Hecht Fabian, Rossetti Leone, Wißmiller Katharina, Bausch Andreas R
Abstract excerpt
UNLABELLED: Structural adaptability is a pivotal requirement of cytoskeletal structures, enabling their reorganization to meet the cellular needs. Shear stress, for instance, results in large morphological network changes of the human soft epithelial keratin pair K8:K18, and is accompanied by an increase in keratin phosphorylation levels. Yet the mechanisms responsible for the disruption of the network structure...
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