Article
PAK1 and aPKCzeta regulate myosin II-B phosphorylation: a novel signaling pathway regulating filament assembly.
Molecular biology of the cell - 1 Jul 2006
Even-Faitelson Liron, Ravid Shoshana
Abstract excerpt
Many signaling pathways regulate the function of the cellular cytoskeleton. Yet we know very little about the proteins involved in the cross-talk between the signaling and the cytoskeletal systems. Here we show that myosin II-B, an important cytoskeletal protein, resides in a complex with p21-activated kinase 1 (PAK1) and atypical protein kinase C (PKC) zeta (aPKCzeta) and that the interaction between these...
Topics
- Actin Cytoskeleton
- Amino Acid Sequence
- Cytoskeleton
- Epidermal Growth Factor
- Humans
- Immunoprecipitation
- Molecular Sequence Data
- Mutation
- Nonmuscle Myosin Type IIB
- Phosphorylation
- Protein Kinase C