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Article

Complementarity of gluCEST and 1H‐MRS for the study of mouse models of Huntington's disease

21 Mar 2020

Abstract excerpt

Identification of relevant biomarkers is fundamental to understand biological processes of neurodegenerative diseases and to evaluate therapeutic efficacy. Atrophy of brain structures has been proposed as a biomarker, but it provides little information about biochemical events related to the disease. Here, we propose to identify early and relevant biomarkers by combining biological specificity provided by 1H‐MRS...

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PMID: 32198958
DOI: 10.1002/nbm.4301

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