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Article

Neurochemical correlates of caudate atrophy in Huntington's disease.

Movement disorders : official journal of the Movement Disorder Society - 1 Mar 2014

Padowski Jeannie M, Weaver Kurt E, Richards Todd L, Laurino Mercy Y, Samii Ali, Aylward Elizabeth H, Conley Kevin E

Abstract excerpt

The precise pathogenic mechanisms of Huntington's disease (HD) are unknown but can be tested in vivo using proton magnetic resonance spectroscopy ((1)H MRS) to measure neurochemical changes. The objective of this study was to evaluate neurochemical differences in HD gene mutation carriers (HGMCs) versus controls and to investigate relationships among function, brain structure, and neurochemistry in HD. Because...

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Identifiers

PMID: 24442623
DOI: 10.1002/mds.25801
PMCID: PMC3960319

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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