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Article

R6/2 Huntington's disease mice develop early and progressive abnormal brain metabolism and seizures.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 9 May 2012

Cepeda-Prado Efrain, Popp Susanna, Khan Usman, Stefanov Dimitre, Rodríguez Jorge, Menalled Liliana B, Dow-Edwards Diana, Small Scott A, Moreno Herman

Abstract excerpt

A hallmark feature of Huntington's disease pathology is the atrophy of brain regions including, but not limited to, the striatum. Though MRI studies have identified structural CNS changes in several Huntington's disease (HD) mouse models, the functional consequences of HD pathology during the progression of the disease have yet to be investigated using in vivo functional MRI (fMRI). To address this issue, we...

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Identifiers

PMID: 22573668
DOI: 10.1523/JNEUROSCI.0388-12.2012
PMCID: PMC3374973

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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