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Enhanced Hippocampal Spare Capacity in Q175DN Mice Despite Elevated mHTT Aggregation

2024-10-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Huntington’s disease (HD) is a neurodegenerative disease resulting in devastating motor, cognitive, and psychiatric deficits. The striatum is a brain region that controls movement and some forms of cognition and is most significantly impacted in HD. However, despite well-documented deficits in learning and memory in HD, knowledge of the potential implication of other brain r...

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Literature Corpus work
5dabe203-e814-52ee-89b4-acfe58cd2555
DOI
10.1101/2024.10.14.618355
Open publication

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Enhanced Hippocampal Spare Capacity in Q175DN Mice Despite Elevated mHTT AggregationDOI 10.1101/2024.10.14.618355
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