Article
RNAi pathways repress reprogramming of C. elegans germ cells during heat stress.
Nucleic acids research - 7 May 2020
Rogers Alicia K, Phillips Carolyn M
Abstract excerpt
Repression of cellular reprogramming in germ cells is critical to maintaining cell fate and fertility. When germ cells mis-express somatic genes they can be directly converted into other cell types, resulting in loss of totipotency and reproductive potential. Identifying the molecular mechanisms that coordinate these cell fate decisions is an active area of investigation. Here we show that RNAi pathways play a...
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