Article
The Stress Granule RNA-Binding Protein TIAR-1 Protects Female Germ Cells from Heat Shock in Caenorhabditis elegans.
G3 (Bethesda, Md.) - 7 Apr 2016
Huelgas-Morales Gabriela, Silva-García Carlos Giovanni, Salinas Laura S, Greenstein David, Navarro Rosa E
Abstract excerpt
In response to stressful conditions, eukaryotic cells launch an arsenal of regulatory programs to protect the proteome. One major protective response involves the arrest of protein translation and the formation of stress granules, cytoplasmic ribonucleoprotein complexes containing the conserved RNA-binding proteins TIA-1 and TIAR. The stress granule response is thought to preserve mRNA for translation when...
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