Article
Association of CHRNA5 Gene Variants with Crack Cocaine Addiction.
Neuromolecular medicine - 1 Sept 2020
Aroche Angelita P, Rovaris Diego L, Grevet Eugenio H, Stolf Anderson R, Sanvicente-Vieira Breno, Kessler Felix H P, von Diemen Lisia, Grassi-Oliveira Rodrigo, Bau Claiton H D, Schuch Jaqueline B
Abstract excerpt
Genome-wide studies provide increasing evidence of association of genetic variants with different behaviors. However, there is a growing need for replication and subsequent characterization of specific findings. In this sense, the CHRNA5 gene has been associated with nicotine (with genome-wide significance), alcohol and cocaine addictions. So far, this gene has not been evaluated in smoked (crack) cocaine. We...
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