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Article

Common single nucleotide variants underlying drug addiction: more than a decade of research.

Addiction biology - 1 Sept 2015

Bühler Kora-Mareen, Giné Elena, Echeverry-Alzate Victor, Calleja-Conde Javier, de Fonseca Fernando Rodriguez, López-Moreno Jose Antonio

Abstract excerpt

Drug-related phenotypes are common complex and highly heritable traits. In the last few years, candidate gene (CGAS) and genome-wide association studies (GWAS) have identified a huge number of single nucleotide polymorphisms (SNPs) associated with drug use, abuse or dependence, mainly related to alcohol or nicotine. Nevertheless, few of these associations have been replicated in independent studies. The aim of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25603899
DOI: 10.1111/adb.12204

Genes

CGAS
CHRNA3
CHRNA5
CHRNB4
DRD2

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