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Article

Association of Polymorphism CHRNA5 and CHRNA3 Gene in People Addicted to Nicotine.

International journal of environmental research and public health - 23 Aug 2022

Chmielowiec Krzysztof, Chmielowiec Jolanta, Strońska-Pluta Aleksandra, Trybek Grzegorz, Śmiarowska Małgorzata, Suchanecka Aleksandra, Woźniak Grzegorz, Jaroń Aleksandra, Grzywacz Anna

Abstract excerpt

Smoking is a chronic and relapsing addictive trait that harms public health. Among the many identified genetic variants of nicotine dependence, the variants in the CHRNA5/A3/B4 gene cluster on chromosome 15 that encode the α5, α3, and β4 subunits have recently received a lot of attention. Importantly, variants in this gene cluster have been associated with nicotine addiction. Among the many significant variants...

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Share to Genetic Predisposition to Disease
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

Share to Receptors, Nicotinic

Share to Tobacco Use Disorder

Source

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Identifiers

PMID: 36078193
DOI: 10.3390/ijerph191710478
PMCID: PMC9517777

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