Article
Genetic polymorphism in patients with early and late onset of ulcerative colitis.
Wiadomosci lekarskie (Warsaw, Poland : 1960) - 1 Jan 2020
Dorofeyev Andriy E, Dorofeyeva Anna A, Kiriyan Elena A, Rassokhina Olga A, Dynia Yulia Z
Abstract excerpt
OBJECTIVE: The aim was to investigate SNPs of TLR-2,3,4, NOD2/CARD15, JAK-2, and IL-10 in patients with the early and late UC onset. PATIENTS AND METHODS: Matherials and methods: 126 patients with UC were investigated. To assess the predisposition of the early and late UC onset the incidence of the following SNPs: Arg753Gln TLR2 gene, Phe412Leu TLR3 gene, Asp299Gly and Thr399Ile TLR4 gene, C-819T, G-1082A and...
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