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Article

Variations in inflammatory genes as molecular markers for prediction of inflammatory bowel disease occurrence.

Journal of digestive diseases - 1 Dec 2015

Stankovic Biljana, Dragasevic Sanja, Popovic Dragan, Zukic Branka, Kotur Nikola, Sokic-Milutinovic Aleksandra, Alempijevic Tamara, Lukic Snezana, Milosavljevic Tomica, Nikcevic Gordana, Pavlovic Sonja

Abstract excerpt

OBJECTIVE: Research on inflammatory bowel disease (IBD) has highlighted genes involved in the regulation of inflammatory responses as contributors to disease pathogenesis. This study aimed to evaluate the associations between IBD and variations in NOD2, TLR4, TNF-α, IL-6, IL-1β and IL-1RN genes, and to use the genetic data obtained in predictive modeling. METHODS: A total of 167 IBD patients and 101 healthy...

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PMID: 26316104
DOI: 10.1111/1751-2980.12281

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TLR4
TNF
NOD2

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