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Article

Genetic association and phenotypic correlation of TLR4 but not NOD2 variants with Tunisian inflammatory bowel disease.

Journal of digestive diseases - 1 Nov 2017

Feki Sawsan, Bouzid Dorra, Abida Olfa, Chtourou Lassaad, Elloumi Nesrine, Toumi Amina, Hachicha Hend, Amouri Ali, Tahri Nabil, Masmoudi Hatem

Abstract excerpt

OBJECTIVE: The common association between NOD2/CARD15 and TLR4 gene variants with inflammatory bowel disease (IBD) has not been replicated in all studies. We studied the polymorphism of these two genes in Tunisian patients with IBD. METHODS: Polymorphisms of NOD2 (R702W, G908R and L1007fs) and TLR4 (Asp299Gly and Thr399Ile) genes were analyzed in 106 patients with IBD (68 with ulcerative colitis [UC], 38 with...

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Source

Identifiers

PMID: 29055077
DOI: 10.1111/1751-2980.12552

Genes

TLR4
NOD2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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