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Article

Unraveling the transcriptional determinants of liver sinusoidal endothelial cell specialization

2 Mar 2020

Abstract excerpt

Liver sinusoidal endothelial cells (LSECs) are the first liver cells to encounter waste macromolecules, pathogens, and toxins in the blood and are highly specialized. Although some transcription factors are known to play a role in LSEC specialization, information about the specialized LSEC signature and its transcriptional determinants remains incomplete. Here, we show that Musculoaponeurotic Fibrosarcoma...

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PMID: 32116021
DOI: 10.1152/ajpgi.00215.2019

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