Article

Human endogenous retrovirus activation contributes to biliary atresia pathogenesis through re-education of resident macrophages

2022-03-14

Abstract excerpt

Biliary atresia (BA) is a life-threatening neonatal fibro-inflammatory disease characterized by hepatic fibrosis, cirrhosis, and end-stage liver failure. BA is also the most frequent indication of pediatric liver transplantation globally. Despite the devastating condition of BA, the pathogenesis mechanism is unknown. Viral infection has been suggested to be associated with BA, but definitive evidence to support th...

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Literature Corpus work: 49f63991-24e5-5c34-ae45-080ab70a8914
DOI: 10.1101/2022.03.11.483921

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