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Article

Single‐cell and spatial transcriptomics reveal the fibrosis‐related immune landscape of biliary atresia

1 Nov 2022

Abstract excerpt

BACKGROUND: Biliary atresia (BA) is a devastating inflammatory and fibrosing cholangiopathy of neonates with unknown aetiology. We aim to investigate the relationship between these two main characteristics. METHODS: Single-cell RNA sequencing and spatial transcriptomics were performed on liver samples from a cohort of 14 objects (BA: n = 6; control: n = 8). We conducted data integration and cell-type annotation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36333281
DOI: 10.1002/ctm2.1070

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