Article

Liver-specification of human iPSC-derived endothelial cells transplanted into mouse liver

2023-06-29

Abstract excerpt

<h4>ABSTRACT</h4> Liver sinusoidal endothelial cells (LSECs) play an important role in liver development, regeneration and pathophysiology, but the differentiation process that generates their unique tissue-specific phenotype is poorly understood and difficult to study as primary cells are only available in limited quantities. To address this, we hypothesised that human induced pluripotent stem cell (hiPSC)-deriv...

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Literature Corpus work: 0ec3b98d-bca2-5b68-8048-7cd1711a02d5
DOI: 10.1101/2023.06.28.546913

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